- Generic Name: Vigabatrin
- Brand Names: Sabril
- Dosage Form: Oral tablets, Powder for oral solution
- Drug Class: Antiepileptic
What is Sabril?
Sabril, with the generic name Vigabatrin, is an antiepileptic medication used in the treatment of seizures associated with epilepsy. It is primarily prescribed for the management of complex partial seizures and refractory complex partial seizures. Sabril is available in the form of oral tablets and powder for oral solution, providing options for administration.
Indications and Uses:
Sabril is used as an adjunctive therapy in the treatment of epilepsy, particularly for complex partial seizures and refractory complex partial seizures. It is prescribed when other medications have not provided adequate seizure control.
How Does Sabril Work?
The exact mechanism of action of Sabril is not fully understood. However, it is believed to exert its antiepileptic effects by increasing the levels of a brain chemical called gamma-aminobutyric acid (GABA). GABA is an inhibitory neurotransmitter that helps regulate the transmission of electrical signals in the brain. By increasing GABA levels, Sabril may reduce the excessive electrical activity that leads to seizures.
The Benefits of Sabril:
- Sabril can help reduce the frequency and severity of seizures in patients with epilepsy, particularly complex partial seizures and refractory complex partial seizures. This can improve overall quality of life and reduce the risk of injury associated with seizures.
- Sabril is often used as an adjunctive therapy, meaning it is added to the existing antiepileptic regimen to enhance seizure control when other medications have been insufficient.
Warnings and Precautions:
- Vision Changes: Sabril can cause vision changes, including peripheral vision loss or narrowing. Regular eye examinations should be conducted before and during treatment to monitor for any visual abnormalities.
- Psychiatric Effects: Sabril may cause psychiatric side effects, including depression, mood changes, irritability, and aggressive behavior. Inform your healthcare provider if you experience any of these symptoms.
- Pregnancy and Breastfeeding: Sabril may pose risks to fetal development during pregnancy. Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
- Drug Interactions: Inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal supplements, as they may interact with Sabril.
Before Using Sabril:
- Medical History: Discuss your complete medical history, including any past surgeries, medical conditions, or known drug allergies.
- Current Medications: Provide a list of all prescription and over-the-counter medications, vitamins and supplements you are currently taking, as they may interact with Sabril.
How is Sabril Administered?
Sabril is taken orally as directed by your healthcare provider. The dosage and administration instructions will depend on your specific condition and individual needs. Follow your healthcare provider's instructions carefully and take Sabril as directed.
Side Effects of Sabril:
Like any medication, Sabril can cause side effects. Common side effects may include:
- Weight gain
Not everyone will experience these side effects, and they may vary in severity. It is important to report any unusual or persistent side effects to your healthcare provider.
- Storage: Sabril should be stored according to the manufacturer's instructions, typically at room temperature away from light and moisture.
- Disposal: Properly dispose of unused Sabril following local regulations or consult with your healthcare provider or pharmacist for guidance on safe disposal methods.
- Accessibility: Sabril is available by prescription only and should be obtained from licensed healthcare facilities or pharmacies.
- Reporting Adverse Effects: If you experience any adverse effects or have concerns about the medication's safety, report them to your healthcare provider or the local regulatory authority.