• Drug Description: Cabometyx
  • Generic Name: Cabozantinib
  • Brand Name: Cabometyx
  • Dosage Form: Capsules
  • Drug Class: Tyrosine Kinase Inhibitors


Cabometyx 20 mg tablet
Cabometyx 20 mg tablet


Cabometyx 60 mg tablet
Cabometyx 60 mg tablet


Among different Types of Cancer Treatment, Cabometyx, known by its generic name cabozantinib, emerges as a targeted therapy with the potential to reshape the prognosis for patients facing advanced renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC). Let's understand the details about where this drug is used and how to be up to date about its usage.

What is Cabometyx and Its Uses

Cabometyx, classified as a tyrosine kinase inhibitor, operates by blocking specific enzymes implicated in the progression and dissemination of cancer cells. Its primary application lies in the treatment of advanced RCC and HCC in adults, offering a beacon of hope for those navigating the complexities of these challenging diagnoses. Additionally, healthcare professionals may prescribe Cabometyx for thyroid cancer and other malignancies, tailoring its usage to individual patient profiles.

Also Read: 10 Tips To Live Your Life After a Lung Cancer Diagnosis

Cabometyx Side Effects and Warnings

Common Adverse Reactions:

  1. Fatigue, diarrhea, and nausea are frequently reported side effects during Cabometyx treatment.
  2. High blood pressure may also manifest as a common reaction.
  3. Hand-foot syndrome, characterized by painful or swollen palms and soles, is another prevalent occurrence.

Serious Side Effects:

  1. Patients should be vigilant about potential serious side effects, including liver problems.
  2. Bleeding complications and perforations within the digestive system are critical concerns that warrant immediate attention.

Vigilance and Reporting:

  1. Vigilance is essential in recognizing atypical symptoms during Cabometyx treatment.
  2. Immediate reporting of any unusual or severe reactions to healthcare providers is imperative for timely intervention.

The Right Way to Consume Cabometyx

Precision in Administration:

  1. Oral administration is the typical route for Cabometyx, either with or without food.
  2. Adherence to the prescribed dosage and schedule is critical for optimal outcomes.

Open Communication:

  1. Patients should maintain open communication with their healthcare team.
  2. Dosage adjustments may be necessary based on individual response and tolerance levels, and these should only be made under professional guidance.

What to Take Care of Before Taking Cabometyx

Medical History Disclosure:

  1. Before commencing Cabometyx, patients must disclose their medical history to healthcare providers.
  2. Special attention is needed for individuals with a history of liver problems, high blood pressure, or bleeding disorders

Heightened Monitoring:

  1. Those with pre-existing conditions may require heightened monitoring during Cabometyx treatment.
  2. Regular check-ups and communication with healthcare providers ensure proactive management.

Pregnancy and Breastfeeding Considerations:

  1. Pregnant or breastfeeding individuals should engage in a thorough discussion with healthcare providers.
  2. Evaluating potential risks and benefits is crucial in determining the course of action during Cabometyx treatment.

Overdose Symptoms and What to Do

Swift Medical Attention:

  1. In the event of a suspected overdose, seeking swift medical attention is paramount.
  2. Symptoms may include severe fatigue, confusion, difficulty breathing, or fainting.

No Self-adjustment:

  1. Patients should refrain from attempting to self-adjust the dosage in cases of suspected overdose.
  2. Only explicit guidance from a healthcare professional should dictate any changes in medication dosage.

Warnings/What Should I Avoid While Taking Cabometyx

Impaired Alertness:

  1. Please be cautious when engaging in activities requiring heightened alertness, such as driving or operating machinery.
  2. Potential side effects like fatigue or dizziness may compromise one's ability to perform such tasks safely.

Grapefruit Exclusion:

  1. Exclude grapefruit and grapefruit juice from the diet during Cabometyx treatment.
  2. These items can alter drug metabolism, impacting the medication's efficacy.

Well-Balanced Diet:

  1. Maintain a well-balanced diet rich in nutrients to support the body through the challenges of cancer treatment.
  2. Adequate nutrition contributes to overall health and may enhance the body's ability to cope with the rigors of therapy.

Hydration Emphasis:

  1. Please make sure you're healthy during Cabometyx treatment.
  2. Hydration is crucial to counteract potential side effects and promote well-being.

Alcohol Caution:

  1. Approach alcohol consumption with caution and discuss it with healthcare providers.
  2. Alcohol may exacerbate specific side effects of Cabometyx, and its intake should be aligned with professional advice.

Off-label Use for Cabometyx

Professional Evaluation:

  1. Off-label use involves prescribing Cabometyx for purposes not explicitly approved by regulatory authorities.
  2. Healthcare professionals should make such decisions after meticulous evaluation of 
  3. potential benefits against associated risks.

Qualified Oversight:

  1. Off-label use requires vigilant oversight by a qualified healthcare provider.
  2. Monitoring patient response and adjusting treatment plans accordingly is essential for the safe and effective application of Cabometyx.

When to Seek Doctor's Advice

Timely Consultation:

  1. Timely consultation with healthcare providers is crucial for ensuring the efficacy and safety of Cabometyx treatment.
  2. Regular check-ups facilitate ongoing monitoring of treatment response and potential adjustments.

Emergency Symptoms:

  1. Seek immediate medical attention if experiencing severe side effects, such as difficulty breathing, chest pain, or signs of liver problems like jaundice.
  2. Prompt intervention addresses emergent issues and ensures patient well-being.

Transparent Communication:

  1. Maintain transparent communication with healthcare teams about any changes in symptoms or concerns.
  2. Open dialogue enables proactive management of potential challenges and ensures a collaborative approach to patient care.


The cancer treatment landscape is evolving, and Cabometyx has made strides in targeted therapy. Beyond its potential, this medication demands a nuanced understanding, collaboration with healthcare providers, and a proactive approach to managing its complexities. In the journey to conquer cancer, knowledge is an indispensable ally. Awareness of Cabometyx its uses, precautions, and potential outcomes patients, caregivers, and healthcare professionals can navigate this terrain confidently, striving towards improved patient outcomes and enhanced quality of life. Always consult your healthcare professional for personalized advice based on your medical history and condition.



Is Cabometyx (cabozantinib) a chemotherapy drug?

No, Cabometyx diverges from traditional chemotherapy. It selectively blocks specific enzymes as a targeted therapy, offering a more focused approach to impeding cancer cell growth and proliferation.

How long does one have to take it?

The duration of Cabometyx treatment is variable and hinges on factors such as cancer type, stage, and individual response. Compliance with the prescribed treatment plan outlined by healthcare providers is essential for optimal outcomes.

What is the success rate of Cabometyx?

The success rate of Cabometyx is contingent upon multiple variables, including the type and stage of cancer. Regular monitoring through check-ups and imaging tests aids healthcare providers in assessing treatment effectiveness and making informed decisions.

What is the difference between Cabometyx and Cometriq?

Cabometyx and Cometriq share cabozantinib as their active ingredient, but their approved indications differ. Cabometyx is endorsed for advanced RCC and HCC, while Cometriq is specifically green-lighted for medullary thyroid cancer.

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